Hi Phil, the writers (at http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017674/) specifically pointed out that they found 'tendency for greater improvements in oxidative stress markers' in the intermittent (5:2) fasting group compared to the pure calorie restriction group, and noted that this was consistent with the assertion that 5:2 provided 'better disease prevention' (under Discussion/Comparison with other studies). They go on to say that 'declines in long term protein oxidation product aggregates suggest (5:2 fasting) as a possible activator of catabolism and autophagy'. Not sure what that means(!) but I think it's good.
So while their study doesn't prove that 5:2 is better than regular calorie restriction, it certainly doesn't prove that it is no better, either. Unless one reckons that all this cellular stress stuff is just hooey.
So while their study doesn't prove that 5:2 is better than regular calorie restriction, it certainly doesn't prove that it is no better, either. Unless one reckons that all this cellular stress stuff is just hooey.