Studies on intermittent fasting compared
Posted: 04 Feb 2013, 19:54
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The 2 wk of IF in the present study were the same as in the study by Halberg et al (1), in which the subjects fasted every second day for 20 h (Figure 1). Fasting started at 2200 and ended at 1800 the following day. The caloric intake during both diet periods was equal to avoid energy restriction with secondary effects on metabolism. Diversion of calories between carbohydrates, fat, and protein were kept equal as well. To increase comparability, the volunteers ate mainly bread, fruit, and dairy products (60% of daily energy intake) supplemented with liquid meals (40% of daily energy intake): Nutridrink [Nutricia Advanced Medical Nutrition, Zoetermeer, Netherlands; per serving (200 mL): 300 kcal, 12.0 g protein, 36.8 g carbohydrate, and 11.6 g fat].
This change in REE could not be attributed to changes in the traditional glucoregulatory hormones or adiponectin. Neither did we find changes in the thyroid hormones, but this does not take into account possible changes in intracellular differences in triiodothyronine production. The type 2 iodothyronine deiodinase has been implicated in the regulation of energy expenditure and insulin signaling (27). Whether iodothyronine deiodinase changes after IF, as described recently after short-term fasting by Heemstra et al (28), remains to be elucidated.
carorees wrote: They point out that the lack of a difference between the two groups in terms of glucose metabolism in normal weight men with normal glucose metabolism does not necessarily mean that fasting would not benefit people with impaired glucose metabolism of course and that it would be worth examining this.
The caloric intake during both diet periods was equal to avoid energy restriction with secondary effects on metabolism. Diversion of calories between carbohydrates, fat, and protein were kept equal as well.