At the start of April, my doctor reduced my dose to 15 mg, to see if it would help with weight loss. Mirtazapine has known weight gain effects, especially carb cravings and increased appetite. And lo and behold, yes, my appetite and carb cravings are less now! I'm waking early now (5–6 am), but it's proving to be worth it. I don't think I can get off the med entirely, but halving my dose is making a big difference.
What I've found (only 20 days in) is that my weight is starting to go down on 5:2 at last, and mostly stay down in between fast days. I've been on 5:2 for 2 years, and in that time have only managed a ~6 kg loss. I've never managed steady weight loss before — it was always down a bit after a fast day, and the right back up to where I was the days after. So I'm cautiously hopeful!
Anyone else in a similar boat?