loversghost wrote: I'm not sure either but I do remember reading ages ago posts from carorees and her issues with her BP control because of her medication which was an ACE and I remember reading some explanation for why it was happening (if I was savvy enough I'd be able to point you to the discussion but I'm not). Maybe you could pm her and ask?
Sorry for the delay in replying to this: I was away for the weekend.
When I started 5:2 I had high blood pressure controlled by ramipril (an ACE inhibitor), as I lost weight my blood pressure came down until after about 6 months it shot up again. My doctor tested everything possible that might have caused it and every test came back normal. I researched on the internet and found a scientific paper documenting paradoxical increases in blood pressure with certain antihypertensive drugs. This means that some people have an increase in blood pressure when they take tablets designed to lower blood pressure. I found that ACE inhibitors are more likely to cause this. I also found that with weight loss you can get a decrease in renin which is the chemical that starts the chain of chemical reactions resulting in an increase blood pressure when the body detects that blood pressure has fallen. ACE inhibitors act to prevent this chain of reactions taking place which is how they lower blood pressure. If there is low renin this kind of paradoxical increase in BP is more likely. So, I decided to stop taking the ACE inhibitor and my BP started to fall fairly quickly. I have now been off medication for about a year and my BP is in the normal range.
Here is the link to the paper on increased BP with antihypertensive medications:
http://www.ncbi.nlm.nih.gov/pubmed/20725055And here is the link to the paper on renin lowering with weight loss:
http://www.ncbi.nlm.nih.gov/pubmed/17846979