Measured reductions in TDEE and TDEE/kg FFM after weight loss are more due to reductions in non-resting expenditure through increased efficiency of work according to http://ajpregu.physiology.org/content/285/1/R183.long
So not so much a reduced metabolism, as a more efficient organism.
The effects were then largely reversed by injecting Leptin in http://www.jci.org/articles/view/25977
Differences in TDEE could approach 3 twix level
So not so much a reduced metabolism, as a more efficient organism.
The effects were then largely reversed by injecting Leptin in http://www.jci.org/articles/view/25977
Differences in TDEE could approach 3 twix level